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All HER2-negative breast cancer patients need gBRCA testing: cost-effectiveness and clinical benefits

BACKGROUND: The OlympiA trial demonstrated the benefits of adjuvant usage of olaparib for high-risk patients with human epidermal growth factor receptor 2 (HER2)-negative breast cancer (BC) and germline BRCA (gBRCA) mutation. This provoked thoughts on the clinical criteria of gBRCA testing. This stu...

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Detalles Bibliográficos
Autores principales:	Wu, Huai-liang, Luo, Zi-yin, He, Zong-lin, Gong, Yue, Mo, Miao, Ming, Wai-kit, Liu, Guang-yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938252/ https://www.ncbi.nlm.nih.gov/pubmed/36564566 http://dx.doi.org/10.1038/s41416-022-02111-y

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