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Islet amyloid polypeptide does not suppress pancreatic cancer

OBJECTIVES: Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide hormone that declines with diabetes progression. IAPP has been reported to act as a tumour-suppressor in p53-deficient cancers capabl...

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Detalles Bibliográficos
Autores principales: Taylor, Austin J., Panzhinskiy, Evgeniy, Orban, Paul C., Lynn, Francis C., Schaeffer, David F., Johnson, James D., Kopp, Janel L., Verchere, C. Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938314/
https://www.ncbi.nlm.nih.gov/pubmed/36621763
http://dx.doi.org/10.1016/j.molmet.2023.101667

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