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Islet amyloid polypeptide does not suppress pancreatic cancer
OBJECTIVES: Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide hormone that declines with diabetes progression. IAPP has been reported to act as a tumour-suppressor in p53-deficient cancers capabl...
Autores principales: | Taylor, Austin J., Panzhinskiy, Evgeniy, Orban, Paul C., Lynn, Francis C., Schaeffer, David F., Johnson, James D., Kopp, Janel L., Verchere, C. Bruce |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938314/ https://www.ncbi.nlm.nih.gov/pubmed/36621763 http://dx.doi.org/10.1016/j.molmet.2023.101667 |
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