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Structural insights into ribonucleoprotein dissociation by nucleocapsid protein interacting with non-structural protein 3 in SARS-CoV-2

The coronavirus nucleocapsid (N) protein interacts with non-structural protein 3 (Nsp3) to facilitate viral RNA synthesis and stabilization. However, structural information on the N-Nsp3 complex is limited. Here, we report a 2.6 Å crystal structure of the N-terminal domain (NTD) of the N protein in...

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Detalles Bibliográficos
Autores principales: Ni, Xincheng, Han, Yinze, Zhou, Renjie, Zhou, Yanmei, Lei, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938351/
https://www.ncbi.nlm.nih.gov/pubmed/36806252
http://dx.doi.org/10.1038/s42003-023-04570-2

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