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Incidence and clinical significance of FLT3 and nucleophosmin mutation in childhood acute myeloid leukemia in Chile

INTRODUCTION: Acute myeloid leukemia (AML) is a heterogeneous disease and approximately one-third of its carriers do not have evident genetic abnormalities. The mutation of specific molecular markers, such as fms-like tyrosine kinase 3 (FTL3) internal tandem duplication (ITD), FLT3 tyrosine kinase d...

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Detalles Bibliográficos
Autores principales: Cabrera, Maria Elena, Monardes, Virginia, Salgado, Carmen, Cares, Carolina, Gonzalez, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Hematologia e Hemoterapia 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938456/
https://www.ncbi.nlm.nih.gov/pubmed/34690101
http://dx.doi.org/10.1016/j.htct.2021.06.003