Orally administered BZL-sRNA-20 oligonucleotide targeting TLR4 effectively ameliorates acute lung injury in mice

The global COVID-19 pandemic emerged at the end of December 2019. Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are common lethal outcomes of bacterial lipopolysaccharide (LPS), avian influenza virus, and SARS-CoV-2. Toll-like receptor 4 (TLR4) is a key target in the patholo...

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Detalles Bibliográficos
Autores principales: Zhao, Dandan, Qin, Yuhao, Liu, Jiaqi, Tang, Kegong, Lu, Shuaiyao, Liu, Zirui, Lin, Yexuan, Zhang, Cong, Huang, Fengming, Chang, Jiahui, Li, Chang, Tian, Mingyao, Ma, Yiming, Li, Xiaoyun, Zhou, Congzhao, Li, Xiao, Peng, Xiaozhong, Jin, Ningyi, Jiang, Chengyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938506/
https://www.ncbi.nlm.nih.gov/pubmed/36808291
http://dx.doi.org/10.1007/s11427-022-2219-0

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