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Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine
A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans. Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest ma...
Autores principales: | Dickey, Thayne H., Gupta, Richi, McAleese, Holly, Ouahes, Tarik, Orr-Gonzalez, Sachy, Ma, Rui, Muratova, Olga, Salinas, Nichole D., Hume, Jen C. C., Lambert, Lynn E., Duffy, Patrick E., Tolia, Niraj H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938515/ https://www.ncbi.nlm.nih.gov/pubmed/36808125 http://dx.doi.org/10.1038/s41541-023-00619-9 |
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