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Design of a stabilized non-glycosylated Pfs48/45 antigen enables a potent malaria transmission-blocking nanoparticle vaccine

A malaria vaccine that blocks parasite transmission from human to mosquito would be a powerful method of disrupting the parasite lifecycle and reducing the incidence of disease in humans. Pfs48/45 is a promising antigen in development as a transmission blocking vaccine (TBV) against the deadliest ma...

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Detalles Bibliográficos
Autores principales: Dickey, Thayne H., Gupta, Richi, McAleese, Holly, Ouahes, Tarik, Orr-Gonzalez, Sachy, Ma, Rui, Muratova, Olga, Salinas, Nichole D., Hume, Jen C. C., Lambert, Lynn E., Duffy, Patrick E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938515/
https://www.ncbi.nlm.nih.gov/pubmed/36808125
http://dx.doi.org/10.1038/s41541-023-00619-9

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