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WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein
BACKGROUND: Large tumor suppressor kinase 1 (LATS1), one of the predominant components of the Hippo pathway, has been characterized as a key player controlling the proliferation and invasion of cancer cells, including gastric cancer (GC) cells. However, the mechanism by which the functional stabilit...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938551/ https://www.ncbi.nlm.nih.gov/pubmed/36803368 http://dx.doi.org/10.1186/s12964-023-01050-2 |