WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein

BACKGROUND: Large tumor suppressor kinase 1 (LATS1), one of the predominant components of the Hippo pathway, has been characterized as a key player controlling the proliferation and invasion of cancer cells, including gastric cancer (GC) cells. However, the mechanism by which the functional stabilit...

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Detalles Bibliográficos
Autores principales: Zou, Jianping, Zhou, Ling, Le, Yi, Fang, Zhi, Zhong, Min, Nie, Fengting, Wei, Xianpin, Zhang, Xiaomei, Chen, Zhen, Cai, Lingling, Wang, Heng, Xiong, Jianping, Fang, Ziling, Xiang, Xiaojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938551/
https://www.ncbi.nlm.nih.gov/pubmed/36803368
http://dx.doi.org/10.1186/s12964-023-01050-2

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