Cargando…

Design and performance analysis of 3D-printed stiffness gradient femoral scaffold

Studies on 3D-printed porous bone scaffolds mostly focus on materials or structural parameters, while the repair of large femoral defects needs to select appropriate structural parameters according to the needs of different parts. In this paper, a kind of stiffness gradient scaffold design idea is p...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Linlin, Liu, Chang, Deng, Congying, Wang, Xin, Liu, Xiangde, Luo, Maolin, Wang, Shuxian, Liu, Juncai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938570/
https://www.ncbi.nlm.nih.gov/pubmed/36804017
http://dx.doi.org/10.1186/s13018-023-03612-z
_version_ 1784890659951345664
author Liu, Linlin
Liu, Chang
Deng, Congying
Wang, Xin
Liu, Xiangde
Luo, Maolin
Wang, Shuxian
Liu, Juncai
author_facet Liu, Linlin
Liu, Chang
Deng, Congying
Wang, Xin
Liu, Xiangde
Luo, Maolin
Wang, Shuxian
Liu, Juncai
author_sort Liu, Linlin
collection PubMed
description Studies on 3D-printed porous bone scaffolds mostly focus on materials or structural parameters, while the repair of large femoral defects needs to select appropriate structural parameters according to the needs of different parts. In this paper, a kind of stiffness gradient scaffold design idea is proposed. Different structures are selected according to the different functions of different parts of the scaffold. At the same time, an integrated fixation device is designed to fix the scaffold. Finite element method was used to analyze the stress and strain of homogeneous scaffolds and the stiffness gradient scaffolds, and the relative displacement and stress between stiffness gradient scaffolds and bone in the case of integrated fixation and steel plate fixation. The results showed that the stress distribution of the stiffness gradient scaffolds was more uniform, and the strain of host bone tissue was changed greatly, which was beneficial to the growth of bone tissue. The integrated fixation method is more stable, less stress and evenly distributed. Therefore, the integrated fixation device combined with the design of stiffness gradient can repair the large femoral bone defect well.
format Online
Article
Text
id pubmed-9938570
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-99385702023-02-19 Design and performance analysis of 3D-printed stiffness gradient femoral scaffold Liu, Linlin Liu, Chang Deng, Congying Wang, Xin Liu, Xiangde Luo, Maolin Wang, Shuxian Liu, Juncai J Orthop Surg Res Research Article Studies on 3D-printed porous bone scaffolds mostly focus on materials or structural parameters, while the repair of large femoral defects needs to select appropriate structural parameters according to the needs of different parts. In this paper, a kind of stiffness gradient scaffold design idea is proposed. Different structures are selected according to the different functions of different parts of the scaffold. At the same time, an integrated fixation device is designed to fix the scaffold. Finite element method was used to analyze the stress and strain of homogeneous scaffolds and the stiffness gradient scaffolds, and the relative displacement and stress between stiffness gradient scaffolds and bone in the case of integrated fixation and steel plate fixation. The results showed that the stress distribution of the stiffness gradient scaffolds was more uniform, and the strain of host bone tissue was changed greatly, which was beneficial to the growth of bone tissue. The integrated fixation method is more stable, less stress and evenly distributed. Therefore, the integrated fixation device combined with the design of stiffness gradient can repair the large femoral bone defect well. BioMed Central 2023-02-18 /pmc/articles/PMC9938570/ /pubmed/36804017 http://dx.doi.org/10.1186/s13018-023-03612-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Liu, Linlin
Liu, Chang
Deng, Congying
Wang, Xin
Liu, Xiangde
Luo, Maolin
Wang, Shuxian
Liu, Juncai
Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title_full Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title_fullStr Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title_full_unstemmed Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title_short Design and performance analysis of 3D-printed stiffness gradient femoral scaffold
title_sort design and performance analysis of 3d-printed stiffness gradient femoral scaffold
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938570/
https://www.ncbi.nlm.nih.gov/pubmed/36804017
http://dx.doi.org/10.1186/s13018-023-03612-z
work_keys_str_mv AT liulinlin designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT liuchang designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT dengcongying designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT wangxin designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT liuxiangde designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT luomaolin designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT wangshuxian designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold
AT liujuncai designandperformanceanalysisof3dprintedstiffnessgradientfemoralscaffold