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Distinct genome-wide DNA methylation and gene expression signatures in classical monocytes from African American patients with systemic sclerosis

BACKGROUND: Systemic sclerosis (SSc) is a multisystem autoimmune disorder that has an unclear etiology and disproportionately affects women and African Americans. Despite this, African Americans are dramatically underrepresented in SSc research. Additionally, monocytes show heightened activation in...

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Detalles Bibliográficos
Autores principales:	Allen, Peter C., Smith, Sarah, Wilson, Robert C., Wirth, Jena R., Wilson, Nathan H., Baker Frost, DeAnna, Flume, Jonathan, Gilkeson, Gary S., Cunningham, Melissa A., Langefeld, Carl D., Absher, Devin M., Ramos, Paula S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938585/ https://www.ncbi.nlm.nih.gov/pubmed/36803404 http://dx.doi.org/10.1186/s13148-023-01445-5

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