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Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component

BACKGROUND: Whether hip revision with a metaphyseal-fixation femoral stem component can restore the bone mass of the proximal femur remains unclear. The aims of this study were to identify whether the bone mineral density (BMD) of the proximal femur increases following hip revision with a metaphysea...

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Autores principales: Li, Zhijie, Li, Mengnan, Yao, Xiaowei, Liu, Bo, Liu, Sikai, Liu, Zeming, Zhang, Binquan, Han, Yongtai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938707/
https://www.ncbi.nlm.nih.gov/pubmed/36820321
http://dx.doi.org/10.2147/TCRM.S393876
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author Li, Zhijie
Li, Mengnan
Yao, Xiaowei
Liu, Bo
Liu, Sikai
Liu, Zeming
Zhang, Binquan
Han, Yongtai
author_facet Li, Zhijie
Li, Mengnan
Yao, Xiaowei
Liu, Bo
Liu, Sikai
Liu, Zeming
Zhang, Binquan
Han, Yongtai
author_sort Li, Zhijie
collection PubMed
description BACKGROUND: Whether hip revision with a metaphyseal-fixation femoral stem component can restore the bone mass of the proximal femur remains unclear. The aims of this study were to identify whether the bone mineral density (BMD) of the proximal femur increases following hip revision with a metaphyseal-fixation femoral stem and to identify the factors associated with BMD recovery. METHODS: This was a retrospective study involving 36 patients who underwent hip arthroplasty with a metaphyseal-diaphyseal fixation stem (standard length stem) and had indications for hip revision, which was performed with a proximal press-fit short-stem prosthesis for each patient. Dual-energy X-ray absorptiometry (DEXA) was used to obtain, evaluate, and compare the BMD at baseline and one year and two years postoperatively. The proximal femur was divided into several independent areas according to the Gruen zone (Gruen 1 to Gruen 7 from the greater trochanter counterclockwise to the lesser trochanter). Logistic regression analyses were used to assess potential factors significantly associated with an increase in BMD. RESULTS: An increased BMD was obviously identified in the proximal femur. Two years after the surgery, the BMD of the Gruen 1, Gruen 2, Gruen 6, and Gruen 7 areas had increased by 22.6%, 12.6%, 16.2% and 24.2%, respectively, relative to baseline. Three independent risk factors associated with bone mineral density recovery were identified: age (OR=1.100, 95% CI=1.005–1.203, P=0.038), osteoporosis (OR=14.921, 95% CI=1.223–182.101, P=0.034) and fair to poor hip function (OR=13.142, 95% CI=1.024–168.582, P=0.048). CONCLUSION: This study confirms that metaphyseal-fixation stem hip revision can indeed help restore bone mass in the proximal femur, especially in the Gruen 1, Gruen 2, Gruen 6 and Gruen 7 zones. It was also found that advanced age, osteoporosis, and fair to poor hip joint function were three important risk factors affecting the recovery of proximal femur bone mass after surgery. TRIAL REGISTRATION: Retrospectively registered.
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spelling pubmed-99387072023-02-19 Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component Li, Zhijie Li, Mengnan Yao, Xiaowei Liu, Bo Liu, Sikai Liu, Zeming Zhang, Binquan Han, Yongtai Ther Clin Risk Manag Original Research BACKGROUND: Whether hip revision with a metaphyseal-fixation femoral stem component can restore the bone mass of the proximal femur remains unclear. The aims of this study were to identify whether the bone mineral density (BMD) of the proximal femur increases following hip revision with a metaphyseal-fixation femoral stem and to identify the factors associated with BMD recovery. METHODS: This was a retrospective study involving 36 patients who underwent hip arthroplasty with a metaphyseal-diaphyseal fixation stem (standard length stem) and had indications for hip revision, which was performed with a proximal press-fit short-stem prosthesis for each patient. Dual-energy X-ray absorptiometry (DEXA) was used to obtain, evaluate, and compare the BMD at baseline and one year and two years postoperatively. The proximal femur was divided into several independent areas according to the Gruen zone (Gruen 1 to Gruen 7 from the greater trochanter counterclockwise to the lesser trochanter). Logistic regression analyses were used to assess potential factors significantly associated with an increase in BMD. RESULTS: An increased BMD was obviously identified in the proximal femur. Two years after the surgery, the BMD of the Gruen 1, Gruen 2, Gruen 6, and Gruen 7 areas had increased by 22.6%, 12.6%, 16.2% and 24.2%, respectively, relative to baseline. Three independent risk factors associated with bone mineral density recovery were identified: age (OR=1.100, 95% CI=1.005–1.203, P=0.038), osteoporosis (OR=14.921, 95% CI=1.223–182.101, P=0.034) and fair to poor hip function (OR=13.142, 95% CI=1.024–168.582, P=0.048). CONCLUSION: This study confirms that metaphyseal-fixation stem hip revision can indeed help restore bone mass in the proximal femur, especially in the Gruen 1, Gruen 2, Gruen 6 and Gruen 7 zones. It was also found that advanced age, osteoporosis, and fair to poor hip joint function were three important risk factors affecting the recovery of proximal femur bone mass after surgery. TRIAL REGISTRATION: Retrospectively registered. Dove 2023-02-14 /pmc/articles/PMC9938707/ /pubmed/36820321 http://dx.doi.org/10.2147/TCRM.S393876 Text en © 2023 Li et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Li, Zhijie
Li, Mengnan
Yao, Xiaowei
Liu, Bo
Liu, Sikai
Liu, Zeming
Zhang, Binquan
Han, Yongtai
Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title_full Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title_fullStr Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title_full_unstemmed Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title_short Bone Remodelling of the Proximal Femur After Hip Revision with a Metaphyseal-Fixation Femoral Stem Component
title_sort bone remodelling of the proximal femur after hip revision with a metaphyseal-fixation femoral stem component
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938707/
https://www.ncbi.nlm.nih.gov/pubmed/36820321
http://dx.doi.org/10.2147/TCRM.S393876
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