m(5)C-dependent cross-regulation between nuclear reader ALYREF and writer NSUN2 promotes urothelial bladder cancer malignancy through facilitating RABL6/TK1 mRNAs splicing and stabilization

The significance of 5-methylcytosine (m(5)C) methylation in human malignancies has become an increasing focus of investigation. Here, we show that m(5)C regulators including writers, readers and erasers, are predominantly upregulated in urothelial carcinoma of the bladder (UCB) derived from Sun Yat-...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Chen, Ri-xin, Deng, Min-hua, Wei, Wen-su, Zhou, Zhao-hui, Ning, Kang, Li, Yong-hong, Li, Xiang-dong, Ye, Yun-lin, Wen, Jun-hua, Dong, Biao, Zhang, Xue-pei, Liu, Zhuo-wei, Zhou, Fang-jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938871/
https://www.ncbi.nlm.nih.gov/pubmed/36806253
http://dx.doi.org/10.1038/s41419-023-05661-y

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