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The tight junction protein occludin modulates blood–brain barrier integrity and neurological function after ischemic stroke in mice

Blood–brain barrier (BBB) disruption contributes to brain injury and neurological impairment. Tight junctions (TJs) and cell–cell adhesion complexes develop between endothelial cells in the brain to establish and maintain the BBB. Occludin, the first transmembrane protein identified in TJs, has rece...

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Detalles Bibliográficos
Autores principales: Sugiyama, Shintaro, Sasaki, Tsutomu, Tanaka, Hiroo, Yan, Haomin, Ikegami, Takeshi, Kanki, Hideaki, Nishiyama, Kumiko, Beck, Goichi, Gon, Yasufumi, Okazaki, Shuhei, Todo, Kenichi, Tamura, Atsushi, Tsukita, Sachiko, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938878/
https://www.ncbi.nlm.nih.gov/pubmed/36806348
http://dx.doi.org/10.1038/s41598-023-29894-1

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