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The tight junction protein occludin modulates blood–brain barrier integrity and neurological function after ischemic stroke in mice
Blood–brain barrier (BBB) disruption contributes to brain injury and neurological impairment. Tight junctions (TJs) and cell–cell adhesion complexes develop between endothelial cells in the brain to establish and maintain the BBB. Occludin, the first transmembrane protein identified in TJs, has rece...
Autores principales: | Sugiyama, Shintaro, Sasaki, Tsutomu, Tanaka, Hiroo, Yan, Haomin, Ikegami, Takeshi, Kanki, Hideaki, Nishiyama, Kumiko, Beck, Goichi, Gon, Yasufumi, Okazaki, Shuhei, Todo, Kenichi, Tamura, Atsushi, Tsukita, Sachiko, Mochizuki, Hideki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938878/ https://www.ncbi.nlm.nih.gov/pubmed/36806348 http://dx.doi.org/10.1038/s41598-023-29894-1 |
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