Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation

INTRODUCTION: The mechanisms of cognitive impairments in Parkinson’s disease (PD) remain unknown. Accumulating evidence revealed that brain neuroinflammatory response mediated by microglial cells contributes to cognitive deficits in neuropathological conditions and macrophage antigen complex-1 (Mac1...

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Detalles Bibliográficos
Autores principales: Hou, Liyan, Liu, Jianing, Sun, Fuqiang, Huang, Ruixue, Chang, Rui, Ruan, Zhengzheng, Wang, Ying, Zhao, Jie, Wang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938991/
https://www.ncbi.nlm.nih.gov/pubmed/36804009
http://dx.doi.org/10.1186/s12974-023-02732-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938991/
https://www.ncbi.nlm.nih.gov/pubmed/36804009
http://dx.doi.org/10.1186/s12974-023-02732-x

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