Regulatory T cells alleviate myelin loss and cognitive dysfunction by regulating neuroinflammation and microglial pyroptosis via TLR4/MyD88/NF-κB pathway in LPC-induced demyelination

Demyelination occurs in multiple central nervous system (CNS) disorders and is tightly associated with neuroinflammation. Pyroptosis is a form of pro-inflammatory and lytic cell death which has been observed in CNS diseases recently. Regulatory T cells (Tregs) have exhibited immunoregulatory and pro...

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Detalles Bibliográficos
Autores principales: Wang, Yao, Sadike, Dilinuer, Huang, Bo, Li, Ping, Wu, Qiao, Jiang, Na, Fang, Yongkang, Song, Guini, Xu, Li, Wang, Wei, Xie, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9938996/
https://www.ncbi.nlm.nih.gov/pubmed/36803990
http://dx.doi.org/10.1186/s12974-023-02721-0

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