Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass

A 56-year-old woman with past medical history significant for bariatric Roux-en-Y gastric bypass 3 years prior presented for evaluation of an 8-month history of severe hypoglycemia relieved by intake of carbohydrates associated with syncopal episodes. Inpatient workup revealed endogenous hyperinsuli...

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Autores principales: Gottsponer, Josephine A, Baker, David L, Osborn, Tamara, Estrada, Martha M, Giorgakis, Emmanouil, Burdine, Lyle J, Patel, Raj B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939044/
https://www.ncbi.nlm.nih.gov/pubmed/36811071
http://dx.doi.org/10.1093/jscr/rjad050
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author Gottsponer, Josephine A
Baker, David L
Osborn, Tamara
Estrada, Martha M
Giorgakis, Emmanouil
Burdine, Lyle J
Patel, Raj B
author_facet Gottsponer, Josephine A
Baker, David L
Osborn, Tamara
Estrada, Martha M
Giorgakis, Emmanouil
Burdine, Lyle J
Patel, Raj B
author_sort Gottsponer, Josephine A
collection PubMed
description A 56-year-old woman with past medical history significant for bariatric Roux-en-Y gastric bypass 3 years prior presented for evaluation of an 8-month history of severe hypoglycemia relieved by intake of carbohydrates associated with syncopal episodes. Inpatient workup revealed endogenous hyperinsulinemia concerning for insulinoma vs. nesidioblastosis. She successfully underwent pancreaticoduodenectomy (Whipple procedure), and pathology report confirmed scattered low-grade intraepithelial neoplasia within the pancreatic parenchyma consistent with nesidioblastosis. The patient has had satisfactory control of glucose levels 30 days out from surgery.
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spelling pubmed-99390442023-02-20 Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass Gottsponer, Josephine A Baker, David L Osborn, Tamara Estrada, Martha M Giorgakis, Emmanouil Burdine, Lyle J Patel, Raj B J Surg Case Rep Case Report A 56-year-old woman with past medical history significant for bariatric Roux-en-Y gastric bypass 3 years prior presented for evaluation of an 8-month history of severe hypoglycemia relieved by intake of carbohydrates associated with syncopal episodes. Inpatient workup revealed endogenous hyperinsulinemia concerning for insulinoma vs. nesidioblastosis. She successfully underwent pancreaticoduodenectomy (Whipple procedure), and pathology report confirmed scattered low-grade intraepithelial neoplasia within the pancreatic parenchyma consistent with nesidioblastosis. The patient has had satisfactory control of glucose levels 30 days out from surgery. Oxford University Press 2023-02-17 /pmc/articles/PMC9939044/ /pubmed/36811071 http://dx.doi.org/10.1093/jscr/rjad050 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gottsponer, Josephine A
Baker, David L
Osborn, Tamara
Estrada, Martha M
Giorgakis, Emmanouil
Burdine, Lyle J
Patel, Raj B
Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title_full Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title_fullStr Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title_full_unstemmed Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title_short Non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric Roux-en-Y gastric bypass
title_sort non-insulinoma pancreatogenous hypoglycemia syndrome due to nesidioblastosis following bariatric roux-en-y gastric bypass
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939044/
https://www.ncbi.nlm.nih.gov/pubmed/36811071
http://dx.doi.org/10.1093/jscr/rjad050
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