Modulation of intracellular kinase signaling to improve TIL stemness and function for adoptive cell therapy

INTRODUCTION: Adoptive cellular therapy with tumor‐infiltrating lymphocytes (TIL) has demonstrated promising clinical benefits in several solid tumors, but the efficacy of this therapy might be compromised by the “prone‐to‐exhaustion” phenotype of TIL and poor persistence in vivo. This calls for a r...

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Detalles Bibliográficos
Autores principales: Feng, Hao, Qiu, Ling, Shi, Zixiao, Sheng, Yao, Zhao, Peipei, Zhou, Di, Li, Fei, Yu, Hailin, You, Yanan, Wang, Hui, Li, Ming, Zhu, Shurong, Du, Yan, Cui, Jun, Sun, Jingwei, Liu, Yarong, Jiang, Hua, Wu, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939193/
https://www.ncbi.nlm.nih.gov/pubmed/36028997
http://dx.doi.org/10.1002/cam4.5095

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