PRMT6 promotes tumorigenicity and cisplatin response of lung cancer through triggering 6PGD/ENO1 mediated cell metabolism

Metabolic reprogramming is a hallmark of cancer, including lung cancer. However, the exact underlying mechanism and therapeutic potential are largely unknown. Here we report that protein arginine methyltransferase 6 (PRMT6) is highly expressed in lung cancer and is required for cell metabolism, tumo...

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Detalles Bibliográficos
Autores principales: Sun, Mingming, Li, Leilei, Niu, Yujia, Wang, Yingzhi, Yan, Qi, Xie, Fei, Qiao, Yaya, Song, Jiaqi, Sun, Huanran, Li, Zhen, Lai, Sizhen, Chang, Hongkai, Zhang, Han, Wang, Jiyan, Yang, Chenxin, Zhao, Huifang, Tan, Junzhen, Li, Yanping, Liu, Shuangping, Lu, Bin, Liu, Min, Kong, Guangyao, Zhao, Yujun, Zhang, Chunze, Lin, Shu-Hai, Luo, Cheng, Zhang, Shuai, Shan, Changliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939295/
https://www.ncbi.nlm.nih.gov/pubmed/36815049
http://dx.doi.org/10.1016/j.apsb.2022.05.019

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