Bile duct ligation differently regulates protein expressions of organic cation transporters in intestine, liver and kidney of rats through activation of farnesoid X receptor by cholate and bilirubin

Body is equipped with organic cation transporters (OCTs). These OCTs mediate drug transport and are also involved in some disease process. We aimed to investigate whether liver failure alters intestinal, hepatic and renal Oct expressions using bile duct ligation (BDL) rats. Pharmacokinetic analysis...

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Detalles Bibliográficos
Autores principales: Hong, Shijin, Li, Shuai, Meng, Xiaoyan, Li, Ping, Wang, Xun, Su, Mengxiang, Liu, Xiaodong, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939304/
https://www.ncbi.nlm.nih.gov/pubmed/36815051
http://dx.doi.org/10.1016/j.apsb.2022.06.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939304/
https://www.ncbi.nlm.nih.gov/pubmed/36815051
http://dx.doi.org/10.1016/j.apsb.2022.06.010

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