Cargando…

Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy

Detalles Bibliográficos
Autores principales: Wang, Guan, Wu, Yongya, Wu, Chengyong, Shuai, Wen, Jiang, Tingting, Wang, Aoxue, Bu, Faqian, Sun, Qiu, Ouyang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939310/
https://www.ncbi.nlm.nih.gov/pubmed/36815052
http://dx.doi.org/10.1016/j.apsb.2022.10.012
_version_ 1784890818795929600
author Wang, Guan
Wu, Yongya
Wu, Chengyong
Shuai, Wen
Jiang, Tingting
Wang, Aoxue
Bu, Faqian
Sun, Qiu
Ouyang, Liang
author_facet Wang, Guan
Wu, Yongya
Wu, Chengyong
Shuai, Wen
Jiang, Tingting
Wang, Aoxue
Bu, Faqian
Sun, Qiu
Ouyang, Liang
author_sort Wang, Guan
collection PubMed
description
format Online
Article
Text
id pubmed-9939310
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-99393102023-02-21 Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy Wang, Guan Wu, Yongya Wu, Chengyong Shuai, Wen Jiang, Tingting Wang, Aoxue Bu, Faqian Sun, Qiu Ouyang, Liang Acta Pharm Sin B Letter to the Editor Elsevier 2023-01 2022-10-19 /pmc/articles/PMC9939310/ /pubmed/36815052 http://dx.doi.org/10.1016/j.apsb.2022.10.012 Text en © 2022 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Letter to the Editor
Wang, Guan
Wu, Yongya
Wu, Chengyong
Shuai, Wen
Jiang, Tingting
Wang, Aoxue
Bu, Faqian
Sun, Qiu
Ouyang, Liang
Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title_full Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title_fullStr Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title_full_unstemmed Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title_short Rational design and crystallographic analysis of novel isoform-selective TRKA inhibitors for cancer therapy
title_sort rational design and crystallographic analysis of novel isoform-selective trka inhibitors for cancer therapy
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939310/
https://www.ncbi.nlm.nih.gov/pubmed/36815052
http://dx.doi.org/10.1016/j.apsb.2022.10.012
work_keys_str_mv AT wangguan rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT wuyongya rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT wuchengyong rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT shuaiwen rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT jiangtingting rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT wangaoxue rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT bufaqian rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT sunqiu rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy
AT ouyangliang rationaldesignandcrystallographicanalysisofnovelisoformselectivetrkainhibitorsforcancertherapy