Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients

The liver plays a central role in the pharmacokinetics of drugs through drug metabolizing enzymes and transporters. Non-alcoholic steatohepatitis (NASH) causes disease-specific alterations to the absorption, distribution, metabolism, and excretion (ADME) processes, including a decrease in protein ex...

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Detalles Bibliográficos
Autores principales: Marie, Solène, Frost, Kayla L., Hau, Raymond K., Martinez-Guerrero, Lucy, Izu, Jailyn M., Myers, Cassandra M., Wright, Stephen H., Cherrington, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939324/
https://www.ncbi.nlm.nih.gov/pubmed/36815037
http://dx.doi.org/10.1016/j.apsb.2022.08.018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939324/
https://www.ncbi.nlm.nih.gov/pubmed/36815037
http://dx.doi.org/10.1016/j.apsb.2022.08.018

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