Cargando…

Fibronectin and JMJD6 Signature in Circulating Placental Extracellular Vesicles for the Detection of Preeclampsia

Preeclampsia (PE) is a major obstetric complication that is challenging to predict. Currently, there are limited tools to assess placental health/function in crucial gestational periods for diagnosis and early prediction. The glycoprotein fibronectin (FN) is augmented in PE placentae, and associated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alahari, Sruthi, Ausman, Jonathan, Porter, Tyler, Park, Chanho, Pettersson, Ante B V, Klemetti, Miira M, Zhang, Jianhong, Post, Martin, Caniggia, Isabella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939344/ https://www.ncbi.nlm.nih.gov/pubmed/36683415 http://dx.doi.org/10.1210/endocr/bqad013

Ejemplares similares

Distinct Changes in Placental Ceramide Metabolism Characterize Type 1 and 2 Diabetic Pregnancies with Fetal Macrosomia or Preeclampsia
por: Klemetti, Miira M., et al.
Publicado: (2023)

JMJD6 Dysfunction Due to Iron Deficiency in Preeclampsia Disrupts Fibronectin Homeostasis Resulting in Diminished Trophoblast Migration
por: Alahari, Sruthi, et al.
Publicado: (2021)

Dichotomy in hypoxia-induced mitochondrial fission in placental mesenchymal cells during development and preeclampsia: consequences for trophoblast mitochondrial homeostasis
por: Gillmore, Taylor, et al.
Publicado: (2022)

HIF1 inhibitor acriflavine rescues early-onset preeclampsia phenotype in mice lacking placental prolyl hydroxylase domain protein 2
por: Sallais, Julien, et al.
Publicado: (2022)

Ceramide-Induced Lysosomal Biogenesis and Exocytosis in Early-Onset Preeclampsia Promotes Exosomal Release of SMPD1 Causing Endothelial Dysfunction
por: Ermini, Leonardo, et al.
Publicado: (2021)

Augmented trophoblast cell death in preeclampsia can proceed via ceramide-mediated necroptosis
por: Bailey, Liane Jennifer, et al.
Publicado: (2017)

Increased placental mitochondrial fusion in gestational diabetes mellitus: an adaptive mechanism to optimize feto-placental metabolic homeostasis?
por: Abbade, Joelcio, et al.
Publicado: (2020)

Ceramide-induced BOK promotes mitochondrial fission in preeclampsia
por: Ausman, Jonathan, et al.
Publicado: (2018)

Factor inhibiting HIF1–A novel target of SUMOylation in the human placenta
por: Sallais, Julien, et al.
Publicado: (2017)

A Single Sphingomyelin Species Promotes Exosomal Release of Endoglin into the Maternal Circulation in Preeclampsia
por: Ermini, Leonardo, et al.
Publicado: (2017)

Associations of maternal and placental extracellular vesicle miRNA with preeclampsia
por: Aharon, Anat, et al.
Publicado: (2023)

TGFb1 suppresses the activation of distinct dNK subpopulations in preeclampsia
por: Zhang, Jianhong, et al.
Publicado: (2018)

Augmented Placental Protein 13 in Placental-Associated Extracellular Vesicles in Term and Preterm Preeclampsia Is Further Elevated by Corticosteroids
por: Kazatsker, Marina Marks, et al.
Publicado: (2023)

Aggregated transthyretin is specifically packaged into placental nano-vesicles in preeclampsia
por: Tong, Mancy, et al.
Publicado: (2017)

Abnormalities in Oxygen Sensing Define Early and Late Onset Preeclampsia as Distinct Pathologies
por: Rolfo, Alessandro, et al.
Publicado: (2010)

Preeclampsia and Extracellular Vesicles
por: Gilani, Sarwat I., et al.
Publicado: (2016)

An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population
por: Klemetti, Miira, et al.
Publicado: (2011)

Antiphospholipid antibodies increase the levels of mitochondrial DNA in placental extracellular vesicles: Alarmin-g for preeclampsia
por: Tong, Mancy, et al.
Publicado: (2017)

Erratum to “An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population”
por: Klemetti, Miira, et al.
Publicado: (2012)

Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model
por: Chen, Yun, et al.
Publicado: (2023)

Placental Aromatase Is Deficient in Placental Ischemia and Preeclampsia
por: Perez-Sepulveda, Alejandra, et al.
Publicado: (2015)

Placental Vesicles Carry Active Endothelial Nitric Oxide Synthase and Their Activity is Reduced in Preeclampsia
por: Motta-Mejia, Carolina, et al.
Publicado: (2017)

Placental Mitochondrial Abnormalities in Preeclampsia
por: Vangrieken, Philippe, et al.
Publicado: (2021)

An RGS2 3′UTR polymorphism is associated with preeclampsia in overweight women
por: Karppanen, Tiina, et al.
Publicado: (2016)

Aspirin Inhibits Fibronectin Expression and Reverses Fibronectin-Mediated Cell Invasiveness by Activating Akt Signaling in Preeclampsia
por: Su, Mei-Tsz, et al.
Publicado: (2022)

Structural and Functional Characterization of Fibronectin in Extracellular Vesicles From Hepatocytes
por: Li, Xinlei, et al.
Publicado: (2021)

Protein Profiling of Preeclampsia Placental Tissues
por: Shu, Chang, et al.
Publicado: (2014)

Oxidative Stress in Preeclampsia and Placental Diseases
por: Aouache, Rajaa, et al.
Publicado: (2018)

Disruption of Placental Homeostasis Leads to Preeclampsia
por: Nakashima, Akitoshi, et al.
Publicado: (2020)

Placental Mitochondrial Function and Dysfunction in Preeclampsia
por: Jahan, Fahmida, et al.
Publicado: (2023)

Syncytiotrophoblast-Derived Extracellular Vesicles in Pathophysiology of Preeclampsia
por: Han, Cha, et al.
Publicado: (2019)

The biodistribution of placental and fetal extracellular vesicles during pregnancy following placentation
por: Kang, Matthew, et al.
Publicado: (2023)

Placental Peripartum Pathologies in Women with Preeclampsia and Eclampsia
por: Ezeigwe, Chijioke Ogomegbulam, et al.
Publicado: (2018)

The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia
por: Apicella, Clara, et al.
Publicado: (2019)

The Downregulation of Placental Lumican Promotes the Progression of Preeclampsia
por: Liu, Chao, et al.
Publicado: (2021)

Preeclampsia and syncytiotrophoblast membrane extracellular vesicles (STB-EVs)
por: Awoyemi, Toluwalase, et al.
Publicado: (2022)

Assessment of Placental Extracellular Vesicles-Associated Fas Ligand and TNF-Related Apoptosis-Inducing Ligand in Pregnancies Complicated by Early and Late Onset Preeclampsia
por: Ayala-Ramírez, Paola, et al.
Publicado: (2021)

The Novel Protease Activities of JMJD5–JMJD6–JMJD7 and Arginine Methylation Activities of Arginine Methyltransferases Are Likely Coupled
por: Liu, Haolin, et al.
Publicado: (2022)

Fibronectin on circulating extracellular vesicles as a liquid biopsy to detect breast cancer
por: Moon, Pyong-Gon, et al.
Publicado: (2016)

The Placental Innate Immune System Is Altered in Early-Onset Preeclampsia, but Not in Late-Onset Preeclampsia
por: Broekhuizen, Michelle, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7gph8k6k97t1qn49tqq3fu75r5