An interactive web application for processing, correcting, and visualizing genome-wide pooled CRISPR-Cas9 screens

A limitation of pooled CRISPR-Cas9 screens is the high false-positive rate in detecting essential genes arising from copy-number-amplified genomics regions. To solve this issue, we previously developed CRISPRcleanR: a computational method implemented as R/python package and in a dockerized version....

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Detalles Bibliográficos
Autores principales: Vinceti, Alessandro, De Lucia, Riccardo Roberto, Cremaschi, Paolo, Perron, Umberto, Karakoc, Emre, Mauri, Luca, Fernandez, Carlos, Kluczynski, Krzysztof Henryk, Anderson, Daniel Stephen, Iorio, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939378/
https://www.ncbi.nlm.nih.gov/pubmed/36814834
http://dx.doi.org/10.1016/j.crmeth.2022.100373

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