Cargando…

Targeting the m6A mRNA demethylase FTO suppresses vascular endothelial growth factor release and choroidal neovascularization

Detalles Bibliográficos
Autores principales:	Wang, Shao-bin, Nagasaka, Yosuke, Argyle, Dionne, Nagasaka, Ayami, Yerramothu, Praveen, Gelfand, Bradley D., Ambati, Jayakrishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939410/ https://www.ncbi.nlm.nih.gov/pubmed/36801892 http://dx.doi.org/10.1038/s41392-022-01277-4

Ejemplares similares

Voluntary Exercise Suppresses Choroidal Neovascularization in Mice
por: Makin, Ryan D., et al.
Publicado: (2020)

A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
por: Narendran, Siddharth, et al.
Publicado: (2020)

Reduction of human Alzheimer’s disease risk and reversal of mouse model cognitive deficit with nucleoside analog use
por: Magagnoli, Joseph, et al.
Publicado: (2023)

Kamuvudine-9 Protects Retinal Structure and Function in a Novel Model of Experimental Rhegmatogenous Retinal Detachment
por: Huang, Peirong, et al.
Publicado: (2023)

The Learning Curve of Murine Subretinal Injection Among Clinically Trained Ophthalmic Surgeons
por: Huang, Peirong, et al.
Publicado: (2022)

Discovery of novel mRNA demethylase FTO inhibitors against esophageal cancer
por: Qin, Bo, et al.
Publicado: (2022)

The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging
por: Jiang, Zhong-xin, et al.
Publicado: (2021)

m(6)A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade
por: Yang, Seungwon, et al.
Publicado: (2019)

Autophagy of the m(6)A mRNA demethylase FTO is impaired by low-level arsenic exposure to promote tumorigenesis
por: Cui, Yan-Hong, et al.
Publicado: (2021)

Correction: The m6A mRNA demethylase FTO in granulosa cells retards FOS-dependent ovarian aging
por: Jiang, Zhong-xin, et al.
Publicado: (2021)

Nitric oxide inhibits FTO demethylase activity to regulate N(6)-methyladenosine mRNA methylation
por: Kuschman, Hannah Petraitis, et al.
Publicado: (2023)

Substrates of the m(6)A demethylase FTO: FTO-LINE1 RNA axis regulates chromatin state in mESCs
por: Sommerkamp, Pia
Publicado: (2022)

m6A demethylase FTO and osteoporosis: potential therapeutic interventions
por: Huang, Mei, et al.
Publicado: (2023)

Nucleoside reverse transcriptase inhibitors and Kamuvudines inhibit amyloid-β induced retinal pigmented epithelium degeneration
por: Narendran, Siddharth, et al.
Publicado: (2021)

RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes
por: Makin, Ryan D., et al.
Publicado: (2018)

New Therapies of Neovascular AMD—Beyond Anti-VEGFs
por: Yerramothu, Praveen
Publicado: (2018)

N6-methyladenosine demethylase FTO suppressed prostate cancer progression by maintaining CLIC4 mRNA stability
por: Zou, Libin, et al.
Publicado: (2022)

FTO m6A Demethylase in Obesity and Cancer: Implications and Underlying Molecular Mechanisms
por: Azzam, Sarah Kassem, et al.
Publicado: (2022)

A novel inhibitor of N(6)-methyladenosine demethylase FTO induces mRNA methylation and shows anti-cancer activities
por: Xie, Guoyou, et al.
Publicado: (2022)

Chronic Dicer1 deficiency promotes atrophic and neovascular outer retinal pathologies in mice
por: Wright, Charles B., et al.
Publicado: (2020)

RNA N6-methyladenosine demethylase FTO promotes osteoporosis through demethylating Runx2 mRNA and inhibiting osteogenic differentiation
por: Wang, Jing, et al.
Publicado: (2021)

Rational Design and Optimization of m(6)A-RNA Demethylase FTO Inhibitors as Anticancer Agents
por: Huff, Sarah, et al.
Publicado: (2022)

The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma
por: Zhang, Dalin, et al.
Publicado: (2022)

m(6)A demethylase FTO regulate CTNNB1 to promote adipogenesis of chicken preadipocyte
por: Li, Kan, et al.
Publicado: (2022)

Targeting the RNA demethylase FTO for cancer therapy
por: Zhou, Lin-Lin, et al.
Publicado: (2021)

m(6)A-RNA Demethylase FTO Inhibitors Impair Self-Renewal in Glioblastoma Stem Cells
por: Huff, Sarah, et al.
Publicado: (2021)

The role of m(6)A demethylase FTO in chemotherapy resistance mediating acute myeloid leukemia relapse
por: Zhang, Zhi-Wei, et al.
Publicado: (2023)

The Functional Role and Regulatory Mechanism of FTO m(6)A RNA Demethylase in Human Uterine Leiomyosarcoma
por: Yang, Qiwei, et al.
Publicado: (2023)

Compartmentalized citrullination in Muller glial endfeet during retinal degeneration
por: Palko, Sarah I., et al.
Publicado: (2022)

Small-Molecule Inhibitors of the RNA M6A Demethylases FTO Potently Support the Survival of Dopamine Neurons
por: Selberg, Simona, et al.
Publicado: (2021)

m6A demethylase FTO promotes tumor progression via regulation of lipid metabolism in esophageal cancer
por: Duan, Xiaoran, et al.
Publicado: (2022)

The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1
por: Ren, Shuai, et al.
Publicado: (2023)

Demethylase FTO inhibits the development of prostate cancer by upregulating EGR2 expression in an m6A manner
por: WANG, Zhenyu, et al.
Publicado: (2022)

Effect of Posttranslational Modifications on the Structure and Activity of FTO Demethylase
por: Marcinkowski, Michał, et al.
Publicado: (2021)

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing
por: Bartosovic, Marek, et al.
Publicado: (2017)

m6A demethylase FTO suppresses pancreatic cancer tumorigenesis by demethylating PJA2 and inhibiting Wnt signaling
por: Zeng, Juan, et al.
Publicado: (2021)

m(6)A demethylase FTO regulates the apoptosis and inflammation of cardiomyocytes via YAP1 in ischemia-reperfusion injury
por: Ke, Wei-Liang, et al.
Publicado: (2022)

Impact of m6A demethylase (ALKBH5, FTO) genetic polymorphism and expression levels on the development of pulmonary tuberculosis
por: Zhang, Tian-Ping, et al.
Publicado: (2022)

SAT632 The Functional Role And Regulatory Mechanism Of FTO M(6)A RNA Demethylase In Human Uterine Leiomyosarcoma
por: Yang, Qiwei, et al.
Publicado: (2023)

RNA Demethylase FTO Mediated RNA m(6)A Modification Is Involved in Maintaining Maternal-Fetal Interface in Spontaneous Abortion
por: Qiu, Weiyu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0u03e71mjqggsn4bu81hihsfif