In-vivo time course of organ uptake and blood-brain-barrier permeation of poly(L-lactide) and poly(perfluorodecyl acrylate) nanoparticles with different surface properties in unharmed and brain-traumatized rats

BACKGROUND: Traumatic brain injury (TBI) has a dramatic impact on mortality and quality of life and the development of effective treatment strategies is of great socio-economic relevance. A growing interest exists in using polymeric nanoparticles (NPs) as carriers across the blood-brain barrier (BBB...

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Detalles Bibliográficos
Autores principales: Bechinger, Patrick, Serrano Sponton, Lucas, Grützner, Verena, Musyanovych, Anna, Jussen, Daniel, Krenzlin, Harald, Eldahaby, Daniela, Riede, Nicole, Kempski, Oliver, Ringel, Florian, Alessandri, Beat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939480/
https://www.ncbi.nlm.nih.gov/pubmed/36814997
http://dx.doi.org/10.3389/fneur.2023.994877

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