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Pilot study suggests DNA methylation of the glucocorticoid receptor gene (NR3C1) is associated with MDMA-assisted therapy treatment response for severe PTSD

BACKGROUND: Previous research has demonstrated that epigenetic changes in specific hypothalamic-pituitary-adrenal (HPA) genes may predict successful psychotherapy in post-traumatic stress disorder (PTSD). A recent Phase 3 clinical trial reported high efficacy of 3,4-methylenedioxymethamphetamine (MD...

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Detalles Bibliográficos
Autores principales:	Lewis, Candace R., Tafur, Joseph, Spencer, Sophie, Green, Joseph M., Harrison, Charlotte, Kelmendi, Benjamin, Rabin, David M., Yehuda, Rachel, Yazar-Klosinski, Berra, Cahn, Baruch Rael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939628/ https://www.ncbi.nlm.nih.gov/pubmed/36815187 http://dx.doi.org/10.3389/fpsyt.2023.959590

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