Gold(I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting thioredoxin reductase

Multidrug-resistant (MDR) Gram-negative bacteria have become a global threat to human life and health, and novel antibiotics are urgently needed. The thioredoxin (Trx) system can be used as an antibacterial target to combat MDR bacteria. Here, we found that two active gold(I) selenium N-heterocyclic...

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Detalles Bibliográficos
Autores principales: Chen, Xiuli, Sun, Shibo, Huang, Sheng, Yang, Han, Ye, Qing, Lv, Lin, Liang, Yanshan, Shan, Jinjun, Xu, Jianqiang, Liu, Wukun, Ma, Tonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939723/
https://www.ncbi.nlm.nih.gov/pubmed/36758467
http://dx.doi.org/10.1016/j.redox.2023.102621

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