Cargando…
Engineering Rieske oxygenase activity one piece at a time
Enzyme engineering plays a central role in the development of biocatalysts for biotechnology, chemical and pharmaceutical manufacturing, and environmental remediation. Rational design of proteins has historically relied on targeting active site residues to confer a protein with desirable catalytic p...
Autores principales: | Brimberry, Marley, Garcia, Alejandro Arcadio, Liu, Jianxin, Tian, Jiayi, Bridwell-Rabb, Jennifer |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939785/ https://www.ncbi.nlm.nih.gov/pubmed/36410250 http://dx.doi.org/10.1016/j.cbpa.2022.102227 |
Ejemplares similares
-
Leveraging a
Structural Blueprint to Rationally Engineer
the Rieske Oxygenase TsaM
por: Tian, Jiayi, et al.
Publicado: (2023) -
Custom tuning of Rieske oxygenase reactivity
por: Tian, Jiayi, et al.
Publicado: (2023) -
Design principles for site-selective hydroxylation by a Rieske oxygenase
por: Liu, Jianxin, et al.
Publicado: (2022) -
The NADH recycling enzymes TsaC and TsaD regenerate reducing equivalents for Rieske oxygenase chemistry
por: Tian, Jiayi, et al.
Publicado: (2023) -
Structural basis for divergent C–H hydroxylation selectivity in two Rieske oxygenases
por: Lukowski, April L., et al.
Publicado: (2020)