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Anti-aging Effects of Alu Antisense RNA on Human Fibroblast Senescence Through the MEK-ERK Pathway Mediated by KIF15

OBJECTIVE: To investigate whether human short interspersed nuclear element antisense RNA (Alu antisense RNA; Alu asRNA) could delay human fibroblast senescence and explore the underlying mechanisms. METHODS: We transfected Alu asRNA into senescent human fibroblasts and used cell counting kit-8 (CCK-...

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Detalles Bibliográficos
Autores principales: Ji, Ning, Wu, Chong-guang, Wang, Xiao-die, Song, Zhi-xue, Wu, Pei-yuan, Liu, Xin, Feng, Xu, Zhang, Xiang-mei, Wang, Xiu-fang, Lv, Zhan-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Huazhong University of Science and Technology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939868/
https://www.ncbi.nlm.nih.gov/pubmed/36808398
http://dx.doi.org/10.1007/s11596-022-2688-z