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The Role of IL-6 and TMEM100 in Lumbar Discogenic Pain and the Mechanism of the Glycine-Serine-Threonine Metabolic Axis: A Metabolomic and Molecular Biology Study

BACKGROUND: It is well established that discogenic low back pain (DLBP) is often caused by the inflammatory response during intervertebral disc degeneration (IDD). However, it remains unclear how inflammatory mediators such as Interleukin-6 (IL-6) are involved in discogenic pain caused by degenerati...

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Detalles Bibliográficos
Autores principales: Guo, Zhaoyang, Ma, Yuanye, Wang, Yaqing, Xiang, Hongfei, Yang, Shang-You, Guo, Zhu, Wang, Ronghuan, Chen, Wujun, Xing, Dongming, Chen, Bohua, Tao, Hao, Wu, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939909/
https://www.ncbi.nlm.nih.gov/pubmed/36815126
http://dx.doi.org/10.2147/JPR.S400871