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Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient‐derived xenografts

BACKGROUND: Purine nucleoside phosphorylase (PNP) gene transfer represents a promising approach to treatment of head and neck malignancies. We tested recombinant adenovirus already in phase I/II clinical testing and leading‐edge patient‐derived xenografts (PDX) as a means to optimize this therapeuti...

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Detalles Bibliográficos
Autores principales:	Rab, Regina, Ehrhardt, Annette, Achyut, Bhagelu R., Joshi, Disha, Gilbert‐Ross, Melissa, Huang, Chunzi, Floyd, Katharine, Borovjagin, Anton V., Parker, William B., Sorscher, Eric J., Hong, Jeong S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9939994/ https://www.ncbi.nlm.nih.gov/pubmed/36253876 http://dx.doi.org/10.1002/cnr2.1708

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