A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge

Histoplasma capsulatum is a geographically specific dimorphic fungus that can cause a spectrum of diseases. While most cases are asymptomatic pulmonary infections, in severe cases, particularly in immunocompromised patients, disseminated disease can occur. Histoplasmosis in California is limited to...

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Autores principales: Govindarajan, Ameish, Sous, Rowis, Venter, Frederick, Torrico, Tyler, Karapetians, Natalie, Heidari, Arash, Cobos, Everardo, Petersen, Greti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940204/
https://www.ncbi.nlm.nih.gov/pubmed/36799482
http://dx.doi.org/10.1177/23247096231156007
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author Govindarajan, Ameish
Sous, Rowis
Venter, Frederick
Torrico, Tyler
Karapetians, Natalie
Heidari, Arash
Cobos, Everardo
Petersen, Greti
author_facet Govindarajan, Ameish
Sous, Rowis
Venter, Frederick
Torrico, Tyler
Karapetians, Natalie
Heidari, Arash
Cobos, Everardo
Petersen, Greti
author_sort Govindarajan, Ameish
collection PubMed
description Histoplasma capsulatum is a geographically specific dimorphic fungus that can cause a spectrum of diseases. While most cases are asymptomatic pulmonary infections, in severe cases, particularly in immunocompromised patients, disseminated disease can occur. Histoplasmosis in California is limited to only a few case reports. In this article, we describe a rare case of disseminated histoplasmosis in a non-endemic region presenting with diagnostically challenging symptomatology, including altered mental status, status epilepticus, septic shock, and bilateral adrenal masses.
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spelling pubmed-99402042023-02-21 A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge Govindarajan, Ameish Sous, Rowis Venter, Frederick Torrico, Tyler Karapetians, Natalie Heidari, Arash Cobos, Everardo Petersen, Greti J Investig Med High Impact Case Rep Case Report Histoplasma capsulatum is a geographically specific dimorphic fungus that can cause a spectrum of diseases. While most cases are asymptomatic pulmonary infections, in severe cases, particularly in immunocompromised patients, disseminated disease can occur. Histoplasmosis in California is limited to only a few case reports. In this article, we describe a rare case of disseminated histoplasmosis in a non-endemic region presenting with diagnostically challenging symptomatology, including altered mental status, status epilepticus, septic shock, and bilateral adrenal masses. SAGE Publications 2023-02-17 /pmc/articles/PMC9940204/ /pubmed/36799482 http://dx.doi.org/10.1177/23247096231156007 Text en © 2023 American Federation for Medical Research https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Govindarajan, Ameish
Sous, Rowis
Venter, Frederick
Torrico, Tyler
Karapetians, Natalie
Heidari, Arash
Cobos, Everardo
Petersen, Greti
A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title_full A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title_fullStr A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title_full_unstemmed A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title_short A Case of Disseminated Histoplasmosis From California, in the Setting of Secondary Hemophagocytic Lymphohistiocytosis: A Diagnostic Challenge
title_sort case of disseminated histoplasmosis from california, in the setting of secondary hemophagocytic lymphohistiocytosis: a diagnostic challenge
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940204/
https://www.ncbi.nlm.nih.gov/pubmed/36799482
http://dx.doi.org/10.1177/23247096231156007
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