Convection-enhanced delivery of nanoencapsulated gene locoregionally yielding ErbB2/Her2-specific CAR-macrophages for brainstem glioma immunotherapy

Locoregional delivery of chimeric antigen receptor (CAR)-modified T (CAR-T) cells has emerged as a promising strategy for brain tumors. However, the complicated ex vivo cell manufacturing procedures and the rapid progression of the disease have limited its broader applications. Macrophages (MΦs) exh...

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Detalles Bibliográficos
Autores principales: Gao, Lin, Shi, Chongdeng, Yang, Zhenmei, Jing, Weiqiang, Han, Maosen, Zhang, Jing, Zhang, Cai, Tang, Chunwei, Dong, Yuanmin, Liu, Ying, Chen, Chen, Jiang, Xinyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940362/
https://www.ncbi.nlm.nih.gov/pubmed/36805678
http://dx.doi.org/10.1186/s12951-023-01810-9

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