Breast cancer cells that preferentially metastasize to lung or bone are more glycolytic, synthesize serine at greater rates, and consume less ATP and NADPH than parent MDA-MB-231 cells

Gene expression signatures associated with breast cancer metastases suggest that metabolic re-wiring is important for metastatic growth in lungs, bones, and other organs. However, since pathway fluxes depend on additional factors such as ATP demand, allosteric effects, and post-translational modific...

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Detalles Bibliográficos
Autores principales: Jekabsons, Mika B., Merrell, Mollie, Skubiz, Anna G., Thornton, Noah, Milasta, Sandra, Green, Douglas, Chen, Taosheng, Wang, Yan-Hong, Avula, Bharathi, Khan, Ikhlas A., Zhou, Yu-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940388/
https://www.ncbi.nlm.nih.gov/pubmed/36805760
http://dx.doi.org/10.1186/s40170-023-00303-5

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