Sputum bacterial load and bacterial composition correlate with lung function and are altered by long-term azithromycin treatment in children with HIV-associated chronic lung disease

BACKGROUND: Long-term azithromycin (AZM) treatment reduces the frequency of acute respiratory exacerbation in children and adolescents with HIV-associated chronic lung disease (HCLD). However, the impact of this treatment on the respiratory bacteriome is unknown. METHOD: African children with HCLD (...

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Detalles Bibliográficos
Autores principales: Abotsi, Regina E., Dube, Felix S., Rehman, Andrea M., Claassen-Weitz, Shantelle, Xia, Yao, Simms, Victoria, Mwaikono, Kilaza S., Gardner-Lubbe, Sugnet, McHugh, Grace, Ngwira, Lucky G., Kwambana-Adams, Brenda, Heyderman, Robert S., Odland, Jon Ø., Ferrand, Rashida A., Nicol, Mark P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940396/
https://www.ncbi.nlm.nih.gov/pubmed/36803868
http://dx.doi.org/10.1186/s40168-023-01460-x

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