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Survival benefit and biomarker analysis of pyrotinib or pyrotinib plus capecitabine for patients with HER2-positive metastatic breast cancer: a pooled analysis of two phase I studies
BACKGROUND: Pyrotinib, a novel irreversible tyrosine kinase inhibitor (TKI), has demonstrated promising antitumor activity to improve the overall response rate and progression-free survival (PFS) in patients with HER2-positive metastatic breast cancer (MBC). However, the survival data of pyrotinib o...
Autores principales: | Guan, Xiuwen, Ma, Fei, Li, Qiao, Chen, Shanshan, Lan, Bo, Fan, Ying, Wang, Jiayu, Luo, Yang, Cai, Ruigang, Zhang, Pin, Li, Qing, Xu, Binghe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940415/ https://www.ncbi.nlm.nih.gov/pubmed/36803645 http://dx.doi.org/10.1186/s40364-023-00453-0 |
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