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ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking

BACKGROUND: Genome-wide association studies (GWASs) have linked RRBP1 (ribosomal-binding protein 1) genetic variants to atherosclerotic cardiovascular diseases and serum lipoprotein levels. However, how RRBP1 regulates blood pressure is unknown. METHODS: To identify genetic variants associated with...

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Detalles Bibliográficos
Autores principales: Chiu, Chu-Hsuan, Hsuan, Chin-Feng, Lin, Shih-Hua, Hung, Yi-Jen, Hwu, Chii-Min, Hee, Siow-Wey, Lin, Shu-Wha, Fong, Sitt-Wai, Hsieh, Patrick Ching-Ho, Yang, Wei-Shun, Lin, Wei-Chou, Lee, Hsiao-Lin, Hsieh, Meng-Lun, Li, Wen-Yi, Lin, Jou-Wei, Hsu, Chih-Neng, Wu, Vin-Cent, Chuang, Gwo-Tsann, Chang, Yi-Cheng, Chuang, Lee-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940419/
https://www.ncbi.nlm.nih.gov/pubmed/36803854
http://dx.doi.org/10.1186/s12929-023-00905-7