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Amyloid-β accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

BACKGROUND: Astrocytes play a central role in maintaining brain energy metabolism, but are also tightly connected to the pathogenesis of Alzheimer’s disease (AD). Our previous studies demonstrate that inflammatory astrocytes accumulate large amounts of aggregated amyloid-beta (Aβ). However, in which...

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Detalles Bibliográficos
Autores principales:	Zyśk, Marlena, Beretta, Chiara, Naia, Luana, Dakhel, Abdulkhalek, Påvénius, Linnea, Brismar, Hjalmar, Lindskog, Maria, Ankarcrona, Maria, Erlandsson, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940442/ https://www.ncbi.nlm.nih.gov/pubmed/36803838 http://dx.doi.org/10.1186/s12974-023-02722-z

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