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Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial

PURPOSE: To investigate the change pattern of ocular perfusion pressure (OPP) and intra-ocular pressure (IOP) after short-term and long-term aerobic exercise. METHODS: In this prospective, single-masked, randomized clinical trial, 123 patients with a primary open angle glaucoma that locally used pro...

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Autores principales: Ma, Qiu-Yan, Zhou, Jian, Xue, Yu-Xin, Xia, Yan-Ting, Wu, Jian-Guo, Yang, Ying-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940524/
https://www.ncbi.nlm.nih.gov/pubmed/36453320
http://dx.doi.org/10.4103/ijo.IJO_1195_22
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author Ma, Qiu-Yan
Zhou, Jian
Xue, Yu-Xin
Xia, Yan-Ting
Wu, Jian-Guo
Yang, Ying-Xin
author_facet Ma, Qiu-Yan
Zhou, Jian
Xue, Yu-Xin
Xia, Yan-Ting
Wu, Jian-Guo
Yang, Ying-Xin
author_sort Ma, Qiu-Yan
collection PubMed
description PURPOSE: To investigate the change pattern of ocular perfusion pressure (OPP) and intra-ocular pressure (IOP) after short-term and long-term aerobic exercise. METHODS: In this prospective, single-masked, randomized clinical trial, 123 patients with a primary open angle glaucoma that locally used prostaglandin analog alone were randomly divided into the exercise and control groups. In the short-term study, all individuals underwent a cycling exercise at moderate intensity (20% Wmax for 10 minutes) and high intensity (60% Wmax for 5 minutes). During the long-term study, the exercise group is characterized by regular jogging exercise lasting for 30 minutes during 6: 00–10: 00 in the morning for 3 months, with the exercise frequency of at least 20 times per month, and with the intensity reflected by the target heart rate. The control group is designed as a group with irregular exercise. RESULTS: After short-term aerobic exercise, IOP significantly decreased, whereas the ocular perfusion pressure (OPP) significantly increased. The decreasing amplitude of IOP is related to the baseline of IOP, the intensity of exercise, gender, and so on. After 3 months of long-term exercise, the changes in the IOP level of the exercise group indicated a decreasing trend. CONCLUSION: The significant decrement of IOP and the increment of OPP suggest that aerobic exercise is beneficial for patients with primary open-angle glaucoma and appropriate aerobic exercise is appropriate in treating glaucoma patients. TRIAL REGISTRATION: ChiCTR, ChiCTR-TRC-10001055. Registered one October 2010-Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj = 8483
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spelling pubmed-99405242023-02-21 Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial Ma, Qiu-Yan Zhou, Jian Xue, Yu-Xin Xia, Yan-Ting Wu, Jian-Guo Yang, Ying-Xin Indian J Ophthalmol Original Article, Special Focus - Glaucoma PURPOSE: To investigate the change pattern of ocular perfusion pressure (OPP) and intra-ocular pressure (IOP) after short-term and long-term aerobic exercise. METHODS: In this prospective, single-masked, randomized clinical trial, 123 patients with a primary open angle glaucoma that locally used prostaglandin analog alone were randomly divided into the exercise and control groups. In the short-term study, all individuals underwent a cycling exercise at moderate intensity (20% Wmax for 10 minutes) and high intensity (60% Wmax for 5 minutes). During the long-term study, the exercise group is characterized by regular jogging exercise lasting for 30 minutes during 6: 00–10: 00 in the morning for 3 months, with the exercise frequency of at least 20 times per month, and with the intensity reflected by the target heart rate. The control group is designed as a group with irregular exercise. RESULTS: After short-term aerobic exercise, IOP significantly decreased, whereas the ocular perfusion pressure (OPP) significantly increased. The decreasing amplitude of IOP is related to the baseline of IOP, the intensity of exercise, gender, and so on. After 3 months of long-term exercise, the changes in the IOP level of the exercise group indicated a decreasing trend. CONCLUSION: The significant decrement of IOP and the increment of OPP suggest that aerobic exercise is beneficial for patients with primary open-angle glaucoma and appropriate aerobic exercise is appropriate in treating glaucoma patients. TRIAL REGISTRATION: ChiCTR, ChiCTR-TRC-10001055. Registered one October 2010-Retrospectively registered, http://www.chictr.org.cn/showproj.aspx?proj = 8483 Wolters Kluwer - Medknow 2022-12 2022-11-30 /pmc/articles/PMC9940524/ /pubmed/36453320 http://dx.doi.org/10.4103/ijo.IJO_1195_22 Text en Copyright: © 2022 Indian Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article, Special Focus - Glaucoma
Ma, Qiu-Yan
Zhou, Jian
Xue, Yu-Xin
Xia, Yan-Ting
Wu, Jian-Guo
Yang, Ying-Xin
Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title_full Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title_fullStr Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title_full_unstemmed Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title_short Analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: A randomized clinical trial
title_sort analysis of aerobic exercise influence on intraocular pressure and ocular perfusion pressure in patients with primary open-angle glaucoma: a randomized clinical trial
topic Original Article, Special Focus - Glaucoma
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940524/
https://www.ncbi.nlm.nih.gov/pubmed/36453320
http://dx.doi.org/10.4103/ijo.IJO_1195_22
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