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Evaluation of Methods to Detect Shifts in Directional Selection at the Genome Scale
Identifying the footprints of selection in coding sequences can inform about the importance and function of individual sites. Analyses of the ratio of nonsynonymous to synonymous substitutions ([Formula: see text]) have been widely used to pinpoint changes in the intensity of selection, but cannot d...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940701/ https://www.ncbi.nlm.nih.gov/pubmed/36510704 http://dx.doi.org/10.1093/molbev/msac247 |