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The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8(+) T cell differentiation and function

The Aryl hydrocarbon receptor (Ahr) regulates the differentiation and function of CD4(+) T cells; however, its cell-intrinsic role in CD8(+) T cells remains elusive. Herein we show that Ahr acts as a promoter of resident memory CD8(+) T cell (T(RM)) differentiation and function. Genetic ablation of...

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Detalles Bibliográficos
Autores principales: Dean, Joseph W., Helm, Eric Y., Fu, Zheng, Xiong, Lifeng, Sun, Na, Oliff, Kristen N., Muehlbauer, Marcus, Avram, Dorina, Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940759/
https://www.ncbi.nlm.nih.gov/pubmed/36640340
http://dx.doi.org/10.1016/j.celrep.2022.111963