Cargando…
Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma
Cisplatin plus 5-fluorouracil (PF) is used as the standard neoadjuvant chemotherapy (also called preoperative chemotherapy) in the treatment of tongue squamous cell carcinoma (TSCC). Although PF chemotherapy reduces the distant metastasis of TSCC, the five-year survival rate has not significantly im...
Autores principales: | Pan, Shu-Ting, Ye, Fang-Fei, Huang, Gan, Qiu, Jia-Xuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940972/ https://www.ncbi.nlm.nih.gov/pubmed/36814557 http://dx.doi.org/10.1155/2023/8306514 |
Ejemplares similares
-
Curcumin and Plumbagin Synergistically Target the PI3K/Akt/mTOR Pathway: A Prospective Role in Cancer Treatment
por: Ahmad, Iftikhar, et al.
Publicado: (2023) -
Plumbagin induces G(2)/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells
por: Pan, Shu-Ting, et al.
Publicado: (2015) -
Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells
por: Zhou, Zhi-Wei, et al.
Publicado: (2015) -
Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
por: Zhang, Renjie, et al.
Publicado: (2020) -
Plumbagin Suppresses Breast Cancer Progression by Downregulating HIF-1α Expression via a PI3K/Akt/mTOR Independent Pathway under Hypoxic Condition
por: Jampasri, Supawan, et al.
Publicado: (2022)