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Interleukin-6 and Hypoxia Synergistically Promote EMT-Mediated Invasion in Epithelial Ovarian Cancer via the IL-6/STAT3/HIF-1α Feedback Loop

Extensive peritoneal spread and capacity for distant metastasis account for the majority of mortality from epithelial ovarian cancer (EOC). Accumulating evidence shows that interleukin-6 (IL-6) promotes tumor invasion and migration in EOC, although the molecular mechanisms remain to be fully elucida...

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Detalles Bibliográficos
Autores principales: Zhang, Tongshuo, Yang, Jing, Sun, Yang, Song, Jiangnan, Gao, Dandan, Huang, Suhui, Pang, Aibo, Zhang, Jianhui, Wang, Junhong, Wang, Yue, Li, Yanqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940980/
https://www.ncbi.nlm.nih.gov/pubmed/36814597
http://dx.doi.org/10.1155/2023/8334881