Cargando…

Transcription Activation of Rab8A by PEA3 Augments Progression of Esophagus Cancer by Activating the Wnt/β-Catenin Signaling Pathway

BACKGROUND: Rab8A has been reported as an oncogenic gene in breast and cervical cancer. However, the function and molecular mechanism of Rab8A in esophagus cancer has not been reported. METHODS: Rab8A expression was detected by qPCR and western blotting assays, small interference RNA (siRNA) was app...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cai, Shusheng, Liu, Xiumei, Gao, Weiran, Ye, Lianhua, Zhong, Qiming, Zhang, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940983/ https://www.ncbi.nlm.nih.gov/pubmed/36815135 http://dx.doi.org/10.1155/2023/8143581

Ejemplares similares

Wnt/β-Catenin Signaling Activation beyond Robust Nuclear β-Catenin Accumulation in Nondysplastic Barrett’s Esophagus: Regulation via Dickkopf-1()()
por: Lyros, Orestis, et al.
Publicado: (2015)

Rab1A promotes cancer metastasis and radioresistance through activating GSK-3β/Wnt/β-catenin signaling in nasopharyngeal carcinoma
por: Yang, Xian-Zi, et al.
Publicado: (2020)

TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling
por: Zhang, Xiumei, et al.
Publicado: (2020)

Pea3 Transcription Factors and Wnt1-Induced Mouse Mammary Neoplasia
por: Baker, Rebecca, et al.
Publicado: (2010)

Rab8 attenuates Wnt signaling and is required for mesenchymal differentiation into adipocytes
por: Stypulkowski, Ewa, et al.
Publicado: (2021)

Fractalkine aggravates LPS‐induced macrophage activation and acute kidney injury via Wnt/β‐catenin signalling pathway
por: Gong, Qiming, et al.
Publicado: (2021)

LiCl‐induced immunomodulatory periodontal regeneration via the activation of the Wnt/β‐catenin signaling pathway
por: Zheng, Xiumei, et al.
Publicado: (2022)

WNT-1 Signaling Inhibits Apoptosis by Activating β-Catenin/T Cell Factor–Mediated Transcription
por: Chen, Shaoqiong, et al.
Publicado: (2001)

Targets of Wnt/ß-Catenin Transcription in Penile Carcinoma
por: Arya, Manit, et al.
Publicado: (2015)

Cell intrinsic Wnt/β-catenin signaling activation
por: Bernkopf, Dominic B., et al.
Publicado: (2018)

Icariin Augments Bone Formation and Reverses the Phenotypes of Osteoprotegerin-Deficient Mice through the Activation of Wnt/β-Catenin-BMP Signaling
por: Li, Xiao-Feng, et al.
Publicado: (2013)

Loss of DSTYK activates Wnt/β-catenin signaling and glycolysis in lung adenocarcinoma
por: Zhong, Chenxi, et al.
Publicado: (2021)

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
por: Luo, Jing, et al.
Publicado: (2019)

Transcriptional factor 3 binds to sirtuin 1 to activate the Wnt/β-catenin signaling in cervical cancer
por: Yu, Xiao, et al.
Publicado: (2022)

MENA Is a Transcriptional Target of the Wnt/Beta-Catenin Pathway
por: Najafov, Ayaz, et al.
Publicado: (2012)

Transcriptional Regulation of Wnt/β-Catenin Pathway in Colorectal Cancer
por: Bian, Jia, et al.
Publicado: (2020)

Wnt/β-Catenin-Dependent Transcription in Autism Spectrum Disorders
por: Caracci, Mario O., et al.
Publicado: (2021)

LINC02273 Promotes Hepatocellular Carcinoma Progression via Retaining β-Catenin in the Nucleus to Augment Wnt Signaling
por: Peng, Liang, et al.
Publicado: (2022)

Identification of a Novel GRHL3/HOPX/Wnt/β-Catenin Proto-oncogenic Axis in Squamous Cell Carcinoma of the Esophagus
por: Georgy, Smitha Rose, et al.
Publicado: (2022)

Requirement of PEA3 for Transcriptional Activation of FAK Gene in Tumor Metastasis
por: Li, Shufeng, et al.
Publicado: (2013)

Molecular hydrogen suppresses activated Wnt/β-catenin signaling
por: Lin, Yingni, et al.
Publicado: (2016)

Toosendanin inhibits adipogenesis by activating Wnt/β-catenin signaling
por: Chen, Tian-xing, et al.
Publicado: (2018)

Metformin activates Wnt/β-catenin for the treatment of diabetic osteoporosis
por: Huang, Xiaopeng, et al.
Publicado: (2022)

Ca(2+)-mediated Mitochondrial Reactive Oxygen Species Metabolism Augments Wnt/β-Catenin Pathway Activation to Facilitate Cell Differentiation
por: Rharass, Tareck, et al.
Publicado: (2014)

Activating transcription factor 5 (ATF5) promotes tumorigenic capability and activates the Wnt/b-catenin pathway in bladder cancer
por: Zhou, Junhao, et al.
Publicado: (2021)

Caspase 8 Promotes Peripheral Localization and Activation of Rab5
por: Torres, Vicente A., et al.
Publicado: (2008)

Activation of Intracellular Calcium by Multiple Wnt Ligands and Translocation of β-Catenin into the Nucleus: A CONVERGENT MODEL OF Wnt/Ca(2+) AND Wnt/β-CATENIN PATHWAYS
por: Thrasivoulou, Christopher, et al.
Publicado: (2013)

Wnt some lose some: transcriptional governance of stem cells by Wnt/β-catenin signaling
por: Lien, Wen-Hui, et al.
Publicado: (2014)

RAB37 multiple alleles, transcription activation and evolution in mammals
por: Xu, Xu, et al.
Publicado: (2020)

Wnt/β-Catenin Signaling Enhances Cyclooxygenase-2 (COX2) Transcriptional Activity in Gastric Cancer Cells
por: Nuñez, Felipe, et al.
Publicado: (2011)

Transcription factor AP-4 promotes tumorigenic capability and activates the Wnt/β-catenin pathway in hepatocellular carcinoma
por: Song, Junwei, et al.
Publicado: (2018)

Novel interaction of Rab13 and Rab8 with endospanins()
por: Hirvonen, Mirkka J., et al.
Publicado: (2013)

Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism
por: Kawamura, Nobuyuki, et al.
Publicado: (2020)

FOX transcription factors are common regulators of Wnt/β-catenin–dependent gene transcription
por: Moparthi, Lavanya, et al.
Publicado: (2023)

α-Catenin interacts with APC to regulate β-catenin proteolysis and transcriptional repression of Wnt target genes
por: Choi, Seung H., et al.
Publicado: (2013)

The WNT/β‐catenin dependent transcription: A tissue‐specific business
por: Söderholm, Simon, et al.
Publicado: (2020)

LASP2 suppressed malignancy and Wnt/β-catenin signaling pathway activation in bladder cancer
por: Yang, Rongquan, et al.
Publicado: (2018)

Aberrant Activation of the WNT/β-Catenin Signaling Pathway in Lupus Nephritis
por: Wang, Xiao-dong, et al.
Publicado: (2014)

Epigenetic Activation of Wnt/β-Catenin Signaling in NAFLD-Associated Hepatocarcinogenesis
por: Tian, Yuan, et al.
Publicado: (2016)

IL‐8 promotes cell migration through regulating EMT by activating the Wnt/β‐catenin pathway in ovarian cancer
por: Wen, Jirui, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_b4jma38gut28oej06mk7ofq2pg