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Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms

This study aimed to develop a bimodal convolutional neural network (CNN) by co-training grayscale images and scalograms of ECG for cardiovascular disease classification. The bimodal CNN model was developed using a 12-lead ECG database collected from Chapman University and Shaoxing People's Hosp...

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Autores principales: Yoon, Taeyoung, Kang, Daesung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941114/
https://www.ncbi.nlm.nih.gov/pubmed/36804469
http://dx.doi.org/10.1038/s41598-023-30208-8
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author Yoon, Taeyoung
Kang, Daesung
author_facet Yoon, Taeyoung
Kang, Daesung
author_sort Yoon, Taeyoung
collection PubMed
description This study aimed to develop a bimodal convolutional neural network (CNN) by co-training grayscale images and scalograms of ECG for cardiovascular disease classification. The bimodal CNN model was developed using a 12-lead ECG database collected from Chapman University and Shaoxing People's Hospital. The preprocessed database contains 10,588 ECG data and 11 heart rhythms labeled by a specialist physician. The preprocessed one-dimensional ECG signals were converted into two-dimensional grayscale images and scalograms, which are fed simultaneously to the bimodal CNN model as dual input images. The proposed model aims to improve the performance of CVDs classification by making use of ECG grayscale images and scalograms. The bimodal CNN model consists of two identical Inception-v3 backbone models, which were pre-trained on the ImageNet database. The proposed model was fine-tuned with 6780 dual-input images, validated with 1694 dual-input images, and tested on 2114 dual-input images. The bimodal CNN model using two identical Inception-v3 backbones achieved best AUC (0.992), accuracy (95.08%), sensitivity (0.942), precision (0.946) and F1-score (0.944) in lead II. Ensemble model of all leads obtained AUC (0.994), accuracy (95.74%), sensitivity (0.950), precision (0.953), and F1-score (0.952). The bimodal CNN model showed better diagnostic performance than logistic regression, XGBoost, LSTM, single CNN model training with grayscale images alone or with scalograms alone. The proposed bimodal CNN model would be of great help in diagnosing cardiovascular diseases.
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spelling pubmed-99411142023-02-22 Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms Yoon, Taeyoung Kang, Daesung Sci Rep Article This study aimed to develop a bimodal convolutional neural network (CNN) by co-training grayscale images and scalograms of ECG for cardiovascular disease classification. The bimodal CNN model was developed using a 12-lead ECG database collected from Chapman University and Shaoxing People's Hospital. The preprocessed database contains 10,588 ECG data and 11 heart rhythms labeled by a specialist physician. The preprocessed one-dimensional ECG signals were converted into two-dimensional grayscale images and scalograms, which are fed simultaneously to the bimodal CNN model as dual input images. The proposed model aims to improve the performance of CVDs classification by making use of ECG grayscale images and scalograms. The bimodal CNN model consists of two identical Inception-v3 backbone models, which were pre-trained on the ImageNet database. The proposed model was fine-tuned with 6780 dual-input images, validated with 1694 dual-input images, and tested on 2114 dual-input images. The bimodal CNN model using two identical Inception-v3 backbones achieved best AUC (0.992), accuracy (95.08%), sensitivity (0.942), precision (0.946) and F1-score (0.944) in lead II. Ensemble model of all leads obtained AUC (0.994), accuracy (95.74%), sensitivity (0.950), precision (0.953), and F1-score (0.952). The bimodal CNN model showed better diagnostic performance than logistic regression, XGBoost, LSTM, single CNN model training with grayscale images alone or with scalograms alone. The proposed bimodal CNN model would be of great help in diagnosing cardiovascular diseases. Nature Publishing Group UK 2023-02-20 /pmc/articles/PMC9941114/ /pubmed/36804469 http://dx.doi.org/10.1038/s41598-023-30208-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Yoon, Taeyoung
Kang, Daesung
Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title_full Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title_fullStr Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title_full_unstemmed Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title_short Bimodal CNN for cardiovascular disease classification by co-training ECG grayscale images and scalograms
title_sort bimodal cnn for cardiovascular disease classification by co-training ecg grayscale images and scalograms
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941114/
https://www.ncbi.nlm.nih.gov/pubmed/36804469
http://dx.doi.org/10.1038/s41598-023-30208-8
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