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Structure-free antibody paratope similarity prediction for in silico epitope binning via protein language models

Antibodies are an important group of biological molecules that are used as therapeutics and diagnostic tools. Although millions of antibody sequences are available, identifying their structural and functional similarity and their antigen binding sites remains a challenge at large scale. Here, we pre...

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Detalles Bibliográficos
Autores principales: Ghanbarpour, Ahmadreza, Jiang, Min, Foster, Denisa, Chai, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941125/
https://www.ncbi.nlm.nih.gov/pubmed/36824280
http://dx.doi.org/10.1016/j.isci.2023.106036