Assessment of anti-CD20 antibody pre-treatment for augmentation of CAR-T cell therapy in SIV-infected rhesus macaques

During chronic HIV and SIV infections, the majority of viral replication occurs within lymphoid follicles. In a pilot study, infusion of SIV-specific CD4-MBL-CAR-T cells expressing the follicular homing receptor, CXCR5, led to follicular localization of the cells and a reduction in SIV viral loads i...

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Detalles Bibliográficos
Autores principales: Pampusch, Mary S., Sevcik, Emily N., Quinn, Zoe E., Davey, Brianna C., Berg, James M., Gorrell-Brown, Ian, Abdelaal, Hadia M., Rakasz, Eva G., Rendahl, Aaron, Skinner, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941136/
https://www.ncbi.nlm.nih.gov/pubmed/36825014
http://dx.doi.org/10.3389/fimmu.2023.1101446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941136/
https://www.ncbi.nlm.nih.gov/pubmed/36825014
http://dx.doi.org/10.3389/fimmu.2023.1101446

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