A passage-dependent network for estimating the in vitro senescence of mesenchymal stromal/stem cells using microarray, bulk and single cell RNA sequencing

Long-term in vitro culture of human mesenchymal stem cells (MSCs) leads to cell lifespan shortening and growth stagnation due to cell senescence. Here, using sequencing data generated in the public domain, we have established a specific regulatory network of “transcription factor (TF)-microRNA (miRN...

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Detalles Bibliográficos
Autores principales: Yang, Yong, Zhang, Wencheng, Wang, Xicheng, Yang, Jingxian, Cui, Yangyang, Song, Haimeng, Li, Weiping, Li, Wei, Wu, Le, Du, Yao, He, Zhiying, Shi, Jun, Zhang, Jiangnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941187/
https://www.ncbi.nlm.nih.gov/pubmed/36824368
http://dx.doi.org/10.3389/fcell.2023.998666

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