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Single-cell pair-wise relationships untangled by composite embedding model
In multicellular organisms, cell identity and functions are primed and refined through interactions with other surrounding cells. Here, we propose a scalable machine learning method, termed SPRUCE, which is designed to systematically ascertain common cell-cell communication patterns embedded in sing...
Autores principales: | Subedi, Sishir, Park, Yongjin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941206/ https://www.ncbi.nlm.nih.gov/pubmed/36824286 http://dx.doi.org/10.1016/j.isci.2023.106025 |
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