Activation and inhibition of the C-terminal kinase domain of p90 ribosomal S6 kinases

The p90 ribosomal S6 kinases (RSKs) contain two distinct catalytic kinase domains, the N-terminal and C-terminal kinase domains (NTKD and CTKD, respectively). The activation of CTKD is regulated by phosphorylation by extracellular signal–regulated kinase (ERK1/2) and an autoinhibitory αL helix. Thro...

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Detalles Bibliográficos
Autores principales: Fruergaard, Marlene Uglebjerg, Nielsen, Christine Juul Fælled, Kjeldsen, Cecilia Rosada, Iversen, Lars, Andersen, Jacob Lauwring, Nissen, Poul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941302/
https://www.ncbi.nlm.nih.gov/pubmed/36806093
http://dx.doi.org/10.26508/lsa.202201425

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941302/
https://www.ncbi.nlm.nih.gov/pubmed/36806093
http://dx.doi.org/10.26508/lsa.202201425

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